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Compound Detail

CHEMBL3288081

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C=C(CO)[C@@H]1CC[C@@]2(C)[C@H]1[C@H]1CC[C@@H]3[C@@]4(C)CC[C@H](OS(=O)(=O)[O-])C(C)(C)[C@@H]4CC[C@@]3(C)[C@]1(C)C[C@@H]2OS(=O)(=O)[O-].[Na+].[Na+]

Basic Information

ChEMBL ID CHEMBL3288081
Phase Preclinical
Structure Type MOL
InChI Key KUHXETQLAYFIQG-CTNMRGLWSA-L
Parent Compound CHEMBL3306915
Active Moiety CHEMBL3306915
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

618.9
MW (Da)
5.62
ALogP
7
HBA
3
HBD
147.4
PSA (Ų)
0.25
QED
2
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C30H48Na2O9S2
MW 662.82
Aromatic Rings 0
Heavy Atoms 41
NP-Likeness 2.44

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
24835788 10.1016/j.bmc.2014.04.050 Acetylcholinesterase 2
24835788 10.1016/j.bmc.2014.04.050 Cholinesterase 2
24835788 10.1016/j.bmc.2014.04.050 Unchecked 1

Data from ChEMBL 36 via Core Engine