Compound Detail
CHEMBL3319275
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Basic Information
| ChEMBL ID | CHEMBL3319275 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RRLCGJPBPYFRNJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
361.8
MW (Da)
3.92
ALogP
5
HBA
2
HBD
80.3
PSA (Ų)
0.74
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.12
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Growth hormone secretagogue receptor type 1 CHEMBL4616 | IC50 | 7.12 | 7.12 | 76.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Growth hormone secretagogue receptor type 1 | IC50 | = | 76.0 | nM | 7.12 | Displacement of [125I]human ghrelin from human GHS-R1a expressed in HEK cell mem... | 24967667 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24967667 | 10.1021/jm500610n | Growth hormone secretagogue receptor type 1 | 2 |
| 24967667 | 10.1021/jm500610n | No relevant target | 2 |
Data from ChEMBL 36 via Core Engine