Compound Detail
CHEMBL333116
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Basic Information
| ChEMBL ID | CHEMBL333116 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OGAMMKNNYFJESR-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
296.1
MW (Da)
2.16
ALogP
5
HBA
3
HBD
78.3
PSA (Ų)
0.69
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA CHEMBL2093871 | IC50 | 5.05 | 5.05 | 9000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA | IC50 | = | 9000.0 | nM | 5.05 | Binding affinity was determined against ionotropic glutamate receptor AMPA in ra... | 7562904 |
| Glutamate receptor ionotropic, AMPA | IC50 | = | 9000.0 | nM | 5.05 | Binding affinity was determined against ionotropic glutamate receptor AMPA in ra... | 7562904 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7562904 | 10.1021/jm00019a003 | Glutamate receptor ionotropic, AMPA | 2 |
Data from ChEMBL 36 via Core Engine