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Compound Detail

CHEMBL3337768

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CCCC(CCC)C(=O)O[C@H]1[C@H](n2cnc3c(N)ncnc32)O[C@H](CO)[C@@]1(C)O

Basic Information

ChEMBL ID CHEMBL3337768
Phase Preclinical
Structure Type MOL
InChI Key UIZZGMMPIOLAQU-MEQBGZRUSA-N
0
Targets
3
Activities
1
Assay Types
2
PK Parameters
10
Publications
0
Known Names

Molecular Properties

407.5
MW (Da)
1.18
ALogP
10
HBA
3
HBD
145.6
PSA (Ų)
0.55
QED
0
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C19H29N5O5
MW 407.47
Aromatic Rings 2
Heavy Atoms 29
NP-Likeness 1.03

Activity Summary

IC50 3 meas.

Pharmacokinetic Data

Parameter Value Units Species
T1/2 72.0 hr -
T1/2 72.0 hr Bos taurus

Literature References

Data from ChEMBL 36 via Core Engine