Compound Detail
CHEMBL3343991
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Basic Information
| ChEMBL ID | CHEMBL3343991 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BFLKQEFSKSGPPF-AVGNSLFASA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
332.4
MW (Da)
-1.34
ALogP
4
HBA
6
HBD
146.1
PSA (Ų)
0.27
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mas-related G-protein coupled receptor member X1 CHEMBL3341576 | EC50 | 6.3 | 6.3 | 501.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mas-related G-protein coupled receptor member X1 | EC50 | = | 501.19 | nM | 6.3 | Agonist activity at mouse MrgC11 transfected in HEK293 cells by FLIPR assay | 25288495 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25288495 | 10.1016/j.bmc.2014.09.025 | Mas-related G-protein coupled receptor member X1 | 3 |
Data from ChEMBL 36 via Core Engine