Compound Detail
CHEMBL334973
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Cn1c([Se][Se]c2c(C(=O)OC(C)(C)C)c3ccccc3n2C)c(C(=O)OC(C)(C)C)c2ccccc21
Basic Information
| ChEMBL ID | CHEMBL334973 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PWTGGAFLPJCGFH-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
618.5
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.82 | 5.82 | 1500.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 1500.0 | nM | 5.82 | Inhibition of Src tyrosine kinase | 9046331 |
| Unchecked | IC50 | = | 1500.0 | nM | 5.82 | Inhibition of v-src (unknown origin) | 34864496 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9046331 | 10.1021/jm960689b | Epidermal growth factor receptor | 1 |
| 9046331 | 10.1021/jm960689b | Platelet-derived growth factor receptor beta | 1 |
| 9046331 | 10.1021/jm960689b | Unchecked | 1 |
| 9046331 | 10.1021/jm960689b | NIH3T3 | 1 |
| 34864496 | 10.1016/j.bmc.2021.116534 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine