Compound Detail
CHEMBL337311
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Basic Information
| ChEMBL ID | CHEMBL337311 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OAJAFWHLVBVKQH-NYYWCZLTSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
256.3
MW (Da)
3.73
ALogP
2
HBA
0
HBD
26.3
PSA (Ų)
0.62
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.84
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 4.84 | 4.84 | 14400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 14400.0 | nM | 4.84 | Inhibition of [3H]hypoxanthine incorporation in Plasmodium falciparum K1 | 11728189 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11728189 | 10.1021/jm0101747 | Mus musculus | 2 |
| - | 10.1007/s00044-011-9602-8 | Plutella xylostella | 2 |
| 11728189 | 10.1021/jm0101747 | Plasmodium falciparum | 1 |
| 11728189 | 10.1021/jm0101747 | Unchecked | 1 |
| 26204510 | 10.1016/j.ejmech.2015.06.029 | NON-PROTEIN TARGET | 1 |
| 31877539 | 10.1016/j.ejmech.2019.111980 | Bacillus anthracis | 1 |
Data from ChEMBL 36 via Core Engine