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Compound Detail

CHEMBL3403615

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Cc1ccsc1C(=CCCN1CCN(CCON=C(c2ccccc2)c2ccccc2)CC(C(=O)O)C1)c1sccc1C

Basic Information

ChEMBL ID CHEMBL3403615
Phase Preclinical
Structure Type MOL
InChI Key GGISDZXAUGEXSU-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

613.9
MW (Da)
7.04
ALogP
7
HBA
1
HBD
65.4
PSA (Ų)
0.11
QED
2
Ro5 Violations
12
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C35H39N3O3S2
MW 613.85
Aromatic Rings 4
Heavy Atoms 43
NP-Likeness -0.44

Literature References

PubMed DOI Target Context # Activities
25882526 10.1016/j.bmc.2015.03.060 Sodium- and chloride-dependent GABA transporter 1 1
25882526 10.1016/j.bmc.2015.03.060 GABA transporter 2 1
25882526 10.1016/j.bmc.2015.03.060 GABA transporter 3 1
25882526 10.1016/j.bmc.2015.03.060 GABA transporter 4 1

Data from ChEMBL 36 via Core Engine