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Compound Detail

CHEMBL3410426

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Cc1[nH]c2cc([C@@H]3CCCCN3C(=O)c3cc(-c4ccccc4)ccc3NS(C)(=O)=O)nn2c(=O)c1C

Basic Information

ChEMBL ID CHEMBL3410426
Phase Preclinical
Structure Type MOL
InChI Key DKGGVLLARGAWEO-DEOSSOPVSA-N
0
Targets
0
Activities
0
Assay Types
1
PK Parameters
5
Publications
0
Known Names

Molecular Properties

519.6
MW (Da)
4.05
ALogP
6
HBA
2
HBD
116.6
PSA (Ų)
0.41
QED
1
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C27H29N5O4S
MW 519.63
Aromatic Rings 4
Heavy Atoms 37
NP-Likeness -1.30

Pharmacokinetic Data

Parameter Value Units Species
Fu 0.006 - Homo sapiens

Literature References

PubMed DOI Target Context # Activities
25574686 10.1021/jm5017768 ADMET 4
25574686 10.1021/jm5017768 Respiratory syncytial virus 1
25574686 10.1021/jm5017768 No relevant target 1
25574686 10.1021/jm5017768 Plasma 1
25574686 10.1021/jm5017768 MT4 1

Data from ChEMBL 36 via Core Engine