Compound Detail
CHEMBL341050
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL341050 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SUVNEFNZAWETBP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
207.4
MW (Da)
3.47
ALogP
1
HBA
1
HBD
26.0
PSA (Ų)
0.74
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate [NMDA] receptor CHEMBL2094124 | Ki | 6.72 | 6.72 | 190.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate [NMDA] receptor | Ki | = | 190.0 | nM | 6.72 | The compound was tested for its ability to block PCP N-methyl-D-aspartate glutam... | 9464369 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7086822 | 10.1021/jm00343a010 | Mus musculus | 5 |
| 7086822 | 10.1021/jm00343a010 | No relevant target | 2 |
| 9464369 | 10.1021/jm9704412 | Glutamate [NMDA] receptor | 1 |
Data from ChEMBL 36 via Core Engine