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Compound Detail

CHEMBL3422281

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O=C1c2c(cc(O)c([C@@H]3C(=O)c4c(O)cc(O)cc4O[C@H]3c3ccc(O)c(O)c3)c2O)O[C@H](c2ccc(O)c(O)c2)[C@H]1O

Basic Information

ChEMBL ID CHEMBL3422281
Phase Preclinical
Structure Type MOL
InChI Key BPKGZLQVBQRSMK-QVDUQQMDSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

590.5
MW (Da)
3.11
ALogP
13
HBA
9
HBD
234.7
PSA (Ų)
0.16
QED
3
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C30H22O13
MW 590.49
Aromatic Rings 4
Heavy Atoms 43
NP-Likeness 1.78

Activity Summary

EC50 1 meas. best 5.07

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
No relevant target
CHEMBL2362975
EC50 5.07 5.07 8500.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
No relevant target EC50 = 8500.0 nM 5.07 Antioxidant activity assessed as H2O2 scavenging activity after 15 mins 25625705

Literature References

PubMed DOI Target Context # Activities
25625705 10.1021/np5007873 No relevant target 5

Data from ChEMBL 36 via Core Engine