Compound Detail
CHEMBL345346
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Basic Information
| ChEMBL ID | CHEMBL345346 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WIQGWZWXZQTAOO-XBXARRHUSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
302.3
MW (Da)
0.20
ALogP
8
HBA
4
HBD
122.1
PSA (Ų)
0.62
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human gammaherpesvirus 4 CHEMBL613124 | EC50 | 6.52 | 6.52 | 300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human gammaherpesvirus 4 | EC50 | = | 300.0 | nM | 6.52 | In vitro effective concentration required to inhibit Epstein-Barr virus (EBV) re... | 14736238 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14736238 | 10.1021/jm030316s | Human betaherpesvirus 5 | 3 |
| 14736238 | 10.1021/jm030316s | Human gammaherpesvirus 4 | 3 |
| 14736238 | 10.1021/jm030316s | MEF | 2 |
| 14736238 | 10.1021/jm030316s | HFF | 1 |
| 14736238 | 10.1021/jm030316s | Human alphaherpesvirus 3 | 1 |
| 14736238 | 10.1021/jm030316s | Hepatitis B virus | 1 |
| 14736238 | 10.1021/jm030316s | HepG2 | 1 |
Data from ChEMBL 36 via Core Engine