Compound Detail
CHEMBL349065
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Basic Information
| ChEMBL ID | CHEMBL349065 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BBJIQUPJSOZDPW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
487.4
MW (Da)
5.27
ALogP
7
HBA
1
HBD
79.6
PSA (Ų)
0.43
QED
1
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | IC50 | 6.66 | 6.66 | 220.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Proto-oncogene tyrosine-protein kinase Src | IC50 | = | 220.0 | nM | 6.66 | Inhibitory activity against human c-Src Kinase was measured using ELISA assay | 11262092 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11262092 | 10.1021/jm000420z | Proto-oncogene tyrosine-protein kinase Src | 2 |
| 11262092 | 10.1021/jm000420z | Tyrosine-protein kinase Fyn | 1 |
Data from ChEMBL 36 via Core Engine