Compound Detail
CHEMBL349855
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL349855 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UGJRVXUXQJLQRP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
246.3
MW (Da)
1.70
ALogP
6
HBA
2
HBD
84.4
PSA (Ų)
0.84
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 10.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Purine nucleoside phosphorylase CHEMBL4338 | IC50 | 10.52 | 10.52 | 0.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Purine nucleoside phosphorylase | IC50 | = | 0.03 | nM | 10.52 | Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme f... | 8421291 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8421291 | 10.1021/jm00053a008 | Purine nucleoside phosphorylase | 1 |
Data from ChEMBL 36 via Core Engine