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Compound Detail

CHEMBL356213

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CCCCC/C=C\C/C=C\CCCCCCCC(=O)N[C@H](C)CO

Basic Information

ChEMBL ID CHEMBL356213
Phase Preclinical
Structure Type MOL
InChI Key ADRRUPVKLINJKD-FNUGXZCYSA-N
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

337.6
MW (Da)
5.30
ALogP
2
HBA
2
HBD
49.3
PSA (Ų)
0.30
QED
1
Ro5 Violations
16
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C21H39NO2
MW 337.55
Aromatic Rings 0
Heavy Atoms 24
NP-Likeness 0.65

Activity Summary

Ki 3 meas. best 4.68

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Cannabinoid receptor 1
CHEMBL3571
Ki 4.68 4.68 21000.0 2
Cannabinoid receptor 2
CHEMBL5373
Ki 4.68 4.68 21000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
9876105 10.1021/jm970257g Cannabinoid receptor 1 2
21257314 10.1016/j.bmc.2010.12.046 HaCaT 2
9876105 10.1021/jm970257g Cannabinoid receptor 2 1

Data from ChEMBL 36 via Core Engine