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Compound Detail

CHEMBL3581265

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N=C(N)NCCC[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O

Basic Information

ChEMBL ID CHEMBL3581265
Phase Preclinical
Structure Type BOTH
InChI Key AVNDVFCGYOONJV-FXSYQQGGSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

769.9
MW (Da)
-0.20
ALogP
8
HBA
11
HBD
280.7
PSA (Ų)
0.07
QED
2
Ro5 Violations
12
Rot. Bonds

Drug Information

Molecule Type Protein
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C39H51N11O6
MW 769.91
Aromatic Rings 3
Heavy Atoms 56
NP-Likeness 0.50

Literature References

PubMed DOI Target Context # Activities
26042340 10.1021/acs.jmedchem.5b00216 Atypical chemokine receptor 3 1
26042340 10.1021/acs.jmedchem.5b00216 C-X-C chemokine receptor type 4 1

Data from ChEMBL 36 via Core Engine