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Compound Detail

CHEMBL3581421

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CC(=O)O[C@@H]1[C@H](O)[C@H]2C(C)(C)[C@H](OC(C)=O)C[C@H](OC(C)=O)[C@]2(C)[C@H]2CC[C@]3(C)C(=CC[C@H]3c3ccoc3)[C@]12C

Basic Information

ChEMBL ID CHEMBL3581421
Phase Preclinical
Structure Type MOL
InChI Key YEBMPMSCNHMQNX-GTOBVWRNSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
6
Publications
0
Known Names

Molecular Properties

556.7
MW (Da)
5.34
ALogP
8
HBA
1
HBD
112.3
PSA (Ų)
0.30
QED
2
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C32H44O8
MW 556.70
Aromatic Rings 1
Heavy Atoms 40
NP-Likeness 3.03

Literature References

PubMed DOI Target Context # Activities
25798528 10.1021/np501057f Tobacco mosaic virus 4
25798528 10.1021/np501057f HL-60 1
25798528 10.1021/np501057f SMMC-7721 1
25798528 10.1021/np501057f A549 1
25798528 10.1021/np501057f MCF7 1
25798528 10.1021/np501057f SW480 1

Data from ChEMBL 36 via Core Engine