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Compound Detail

CHEMBL358850

D-LACTIC ACID
🧪 Phase III
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🧪 Phase III
C[C@@H](O)C(=O)O

Basic Information

ChEMBL ID CHEMBL358850
Name D-LACTIC ACID
Phase Phase III
Structure Type MOL
InChI Key JVTAAEKCZFNVCJ-UWTATZPHSA-N

Known Names

D-(-)-lactic acid D-lactic acid Lactic acid, d- Propanoic acid, 2-hydroxy-, (2r)-
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
20
Publications
4
Known Names

Molecular Properties

90.1
MW (Da)
-0.55
ALogP
2
HBA
2
HBD
57.5
PSA (Ų)
0.45
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Single Enantiomer

Flags

Natural Product

Extended Properties

Molecular Formula C3H6O3
MW 90.08
Aromatic Rings 0
Heavy Atoms 6
NP-Likeness 0.53

Activity Summary

Ki 1 meas.

Literature References

PubMed DOI Target Context # Activities
22194678 10.1371/journal.pcbi.1002310 Hepatotoxicity 14
14610227 10.1124/jpet.103.060194 Solute carrier organic anion transporter family member 2B1 2
11278508 10.1074/jbc.m009462200 Monocarboxylate transporter 10 2
9374487 10.1074/jbc.272.48.30096 Monocarboxylate transporter 1 1
32388280 10.1016/j.ejmech.2020.112393 Monocarboxylate transporter 4 1
32388280 10.1016/j.ejmech.2020.112393 Monocarboxylate transporter 1 1
24249037 10.1007/s11095-013-1232-z No relevant target 1
23547775 10.1021/jm400193d Alpha-ketoglutarate-dependent dioxygenase FTO 1
11997326 10.1152/ajprenal.00151.2001 Solute carrier organic anion transporter family member 2A1 1
11827462 10.1006/geno.2001.6678 SLC16A10 protein 1
11101640 10.1111/j.1469-7793.2000.00285.x Monocarboxylate transporter 4 1
10579833 10.1021/jm990361t Unchecked 1
9639576 10.1042/bj3330167 Monocarboxylate transporter 1 1
10417314 10.1042/0264-6021:3410529 Monocarboxylate transporter 2 1
12724351 10.1124/jpet.103.051300 Solute carrier organic anion transporter family member 2B1 1
9786900 10.1074/jbc.273.44.28959 Monocarboxylate transporter 1 1
9786900 10.1074/jbc.273.44.28959 Monocarboxylate transporter 2 1
10579682 10.1211/0022357991776804 Monocarboxylate transporter 1 1
8526936 10.1006/bbrc.1995.2786 Monocarboxylate transporter 1 1
12873507 10.1016/s0960-894x(03)00535-3 NON-PROTEIN TARGET 1

Data from ChEMBL 36 via Core Engine