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Compound Detail

CHEMBL3594159

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C/C(=C/CC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(C(O)C[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)[C@@H]1CC3=O)C(=O)O

Basic Information

ChEMBL ID CHEMBL3594159
Phase Preclinical
Structure Type MOL
InChI Key SAZFHNNKAYSDKP-ZWCQFIPQSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
6
Publications
0
Known Names

Molecular Properties

484.7
MW (Da)
5.90
ALogP
4
HBA
2
HBD
91.7
PSA (Ų)
0.47
QED
1
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C30H44O5
MW 484.68
Aromatic Rings 0
Heavy Atoms 35
NP-Likeness 3.27

Literature References

PubMed DOI Target Context # Activities
26287401 10.1021/acs.jnatprod.5b00331 Unchecked 2
26287401 10.1021/acs.jnatprod.5b00331 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1
26287401 10.1021/acs.jnatprod.5b00331 Sucrase-isomaltase, intestinal 1
26287401 10.1021/acs.jnatprod.5b00331 Acidic alpha-glucosidase 1
26287401 10.1021/acs.jnatprod.5b00331 K562 1
26287401 10.1021/acs.jnatprod.5b00331 PC-3 1

Data from ChEMBL 36 via Core Engine