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Compound Detail

CHEMBL3597148

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CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(N)nc(Cl)nc32)C[C@@H]1O)OC(=O)CCCCCCCCCCCCCCC.[Na+]

Basic Information

ChEMBL ID CHEMBL3597148
Phase Preclinical
Structure Type MOL
InChI Key REKFWVMSZQAEDN-IJOVDALLSA-M
Parent Compound CHEMBL3598238
Active Moiety CHEMBL3598238
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

916.6
MW (Da)
11.26
ALogP
14
HBA
3
HBD
207.4
PSA (Ų)
0.02
QED
3
Ro5 Violations
38
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C45H78ClN5NaO10P
MW 938.56
Aromatic Rings 2
Heavy Atoms 62
NP-Likeness 0.56

Literature References

PubMed DOI Target Context # Activities
25960323 10.1016/j.bmc.2015.04.059 NON-PROTEIN TARGET 1
25960323 10.1016/j.bmc.2015.04.059 K562 1
25960323 10.1016/j.bmc.2015.04.059 MCF7 1

Data from ChEMBL 36 via Core Engine