Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL3613011

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)c3ccccc3N(S(=O)(=O)c3ccc(Br)cc3)S(=O)(=O)c3ccc(Br)cc3)cc1)CC2

Basic Information

ChEMBL ID CHEMBL3613011
Phase Preclinical
Structure Type MOL
InChI Key DQIYNAWJFAUJBY-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
9
Publications
0
Known Names

Molecular Properties

869.6
MW (Da)
7.67
ALogP
8
HBA
1
HBD
122.3
PSA (Ų)
0.14
QED
2
Ro5 Violations
12
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C38H35Br2N3O7S2
MW 869.65
Aromatic Rings 5
Heavy Atoms 52
NP-Likeness -0.95

Literature References

PubMed DOI Target Context # Activities
26197160 10.1016/j.ejmech.2015.06.049 ADMET 5
26197160 10.1016/j.ejmech.2015.06.049 ATP-dependent translocase ABCB1 4
26197160 10.1016/j.ejmech.2015.06.049 Unchecked 2
26197160 10.1016/j.ejmech.2015.06.049 SW-620 1
26197160 10.1016/j.ejmech.2015.06.049 HCT-116 1
26197160 10.1016/j.ejmech.2015.06.049 Hepatocyte 1
26197160 10.1016/j.ejmech.2015.06.049 K562 1
26197160 10.1016/j.ejmech.2015.06.049 Multidrug resistance-associated protein 1 1
26197160 10.1016/j.ejmech.2015.06.049 NON-PROTEIN TARGET 1

Data from ChEMBL 36 via Core Engine