Compound Detail
CHEMBL3621671
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3621671 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HIQDDYPYHODDTQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
313.4
MW (Da)
3.16
ALogP
5
HBA
0
HBD
38.1
PSA (Ų)
0.74
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.27
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| CREB-binding protein CHEMBL5747 | IC50 | 5.27 | 5.27 | 5370.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| CREB-binding protein | IC50 | = | 5370.0 | nM | 5.27 | Inhibition of recombinant human CBP using biotinylated histone H3 (1 to 21 amino... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C4MD00245H | CREB-binding protein | 2 |
| - | 10.1039/C4MD00245H | Histone acetyltransferase KAT2B | 1 |
| - | 10.1039/C4MD00245H | Histone acetyltransferase KAT2A | 1 |
| - | 10.1039/C4MD00245H | Histone acetyltransferase p300 | 1 |
Data from ChEMBL 36 via Core Engine