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Compound Detail

CHEMBL3622002

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Cc1ccc([C@H]2C3=C(OC[C@@H]2[N+](=O)[O-])C(=O)c2ccccc2C3=O)cc1

Basic Information

ChEMBL ID CHEMBL3622002
Phase Preclinical
Structure Type MOL
InChI Key XKGJYJVVCCLUJV-JKSUJKDBSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

349.3
MW (Da)
3.09
ALogP
5
HBA
0
HBD
86.5
PSA (Ų)
0.61
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C20H15NO5
MW 349.34
Aromatic Rings 2
Heavy Atoms 26
NP-Likeness 0.16

Literature References

PubMed DOI Target Context # Activities
- 10.1039/C4MD00371C HL-60 1
- 10.1039/C4MD00371C HCT-116 1
- 10.1039/C4MD00371C OVCAR-8 1
- 10.1039/C4MD00371C SF-295 1
- 10.1039/C4MD00371C PBMC 1

Data from ChEMBL 36 via Core Engine