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Compound Detail

CHEMBL3622003

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O=C1C2=C(C(=O)c3ccccc31)[C@H](c1cccc(Br)c1)[C@@H]([N+](=O)[O-])CO2

Basic Information

ChEMBL ID CHEMBL3622003
Phase Preclinical
Structure Type MOL
InChI Key PGWFLQSTHKGSRU-LSDHHAIUSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

414.2
MW (Da)
3.54
ALogP
5
HBA
0
HBD
86.5
PSA (Ų)
0.55
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C19H12BrNO5
MW 414.21
Aromatic Rings 2
Heavy Atoms 26
NP-Likeness 0.09

Literature References

PubMed DOI Target Context # Activities
- 10.1039/C4MD00371C HL-60 1
- 10.1039/C4MD00371C HCT-116 1
- 10.1039/C4MD00371C OVCAR-8 1
- 10.1039/C4MD00371C SF-295 1
- 10.1039/C4MD00371C PBMC 1

Data from ChEMBL 36 via Core Engine