Compound Detail
CHEMBL3628755
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3628755 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NPYOAANRTJNYEB-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
410.4
MW (Da)
5.16
ALogP
4
HBA
1
HBD
65.0
PSA (Ų)
0.56
QED
1
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 7.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Free fatty acid receptor 1 CHEMBL4422 | EC50 | 7.3 | 7.285 | 49.7 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Free fatty acid receptor 1 | EC50 | = | 49.7 | nM | 7.3 | Agonist activity at human FFA1 receptor expressed in CHO cells assessed as incre... | 26482570 |
| Free fatty acid receptor 1 | EC50 | = | 54.2 | nM | 7.27 | Agonist activity at human FFA1 receptor expressed in CHO cells assessed as incre... | 30082106 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26482570 | 10.1016/j.bmc.2015.10.011 | Free fatty acid receptor 1 | 2 |
| 26482570 | 10.1016/j.bmc.2015.10.011 | No relevant target | 1 |
| 30082106 | 10.1016/j.bmc.2018.07.050 | Free fatty acid receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine