Compound Detail
CHEMBL364506
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2c(c1)n(-c1ccc3c(c1)OCO3)c(=O)n2C
Basic Information
| ChEMBL ID | CHEMBL364506 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FBJKGHHPAQJOII-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
488.9
MW (Da)
3.73
ALogP
8
HBA
1
HBD
83.4
PSA (Ų)
0.42
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.82 | 6.82 | 150.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 150.0 | nM | 6.82 | Inhibition of bovine farnesyl transferase | 15911281 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15911281 | 10.1016/j.bmcl.2005.03.049 | Unchecked | 1 |
| 15911281 | 10.1016/j.bmcl.2005.03.049 | Geranylgeranyl transferase type I | 1 |
| 15911281 | 10.1016/j.bmcl.2005.03.049 | Protein farnesyltransferase | 1 |
Data from ChEMBL 36 via Core Engine