Compound Detail
CHEMBL364512
RISPERIDON Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL364512 |
| Name | RISPERIDON |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WDNMHZRFIIOXOD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
412.5
MW (Da)
2.92
ALogP
6
HBA
1
HBD
59.4
PSA (Ų)
0.84
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Voltage-gated inwardly rectifying potassium channel KCNH2 CHEMBL240 | IC50 | 6.82 | 6.82 | 151.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Voltage-gated inwardly rectifying potassium channel KCNH2 | IC50 | = | 151.36 | nM | 6.82 | Inhibitory concentration against potassium channel HERG | 15911273 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15911273 | 10.1016/j.bmcl.2005.03.080 | Voltage-gated inwardly rectifying potassium channel KCNH2 | 1 |
Data from ChEMBL 36 via Core Engine