Compound Detail
CHEMBL3646108
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Basic Information
| ChEMBL ID | CHEMBL3646108 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UECBGPSHIWJXPJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
311.4
MW (Da)
1.13
ALogP
7
HBA
1
HBD
84.6
PSA (Ų)
0.78
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prolyl hydroxylase EGLN2 CHEMBL3028 | IC50 | 6.3 | 6.3 | 500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prolyl hydroxylase EGLN2 | IC50 | = | 500.0 | nM | 6.3 | Inhibition Assay: Hydroxylated HIF bonds specifically to the von Hippel-Lindau p... | - |
Data from ChEMBL 36 via Core Engine