Compound Detail
CHEMBL3646228
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3646228 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UAWDTSDYMRFDAE-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
311.3
MW (Da)
1.91
ALogP
5
HBA
2
HBD
92.9
PSA (Ų)
0.66
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.29
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Egl nine homolog 1 CHEMBL5697 | IC50 | 5.29 | 5.29 | 5100.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Egl nine homolog 1 | IC50 | = | 5100.0 | nM | 5.29 | Enzyme Assay: The EGLN-1 (or EGLN-3) enzyme activity is determined using mass sp... | - |
| Egl nine homolog 1 | IC50 | = | 5100.0 | nM | 5.29 | Mass Spectrometry Assay : The EGLN-1 (or EGLN-3) enzyme activity is determined u... | - |
Data from ChEMBL 36 via Core Engine