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Compound Detail

CHEMBL365809

BUTANEDIONE
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Basic Information

ChEMBL ID CHEMBL365809
Name BUTANEDIONE
Phase Preclinical
Structure Type MOL
InChI Key QSJXEFYPDANLFS-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
13
Publications
0
Known Names

Molecular Properties

86.1
MW (Da)
0.16
ALogP
2
HBA
0
HBD
34.1
PSA (Ų)
0.43
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C4H6O2
MW 86.09
Aromatic Rings 0
Heavy Atoms 6
NP-Likeness 0.11

Literature References

PubMed DOI Target Context # Activities
15828829 10.1021/jm049011j Liver carboxylesterase 1 2
21733699 10.1016/j.bmc.2011.06.012 Liver carboxylesterase 1 2
- 10.6019/CHEMBL4495565 SARS-CoV-2 2
15828829 10.1021/jm049011j Cocaine esterase 1
15828829 10.1021/jm049011j Acetylcholinesterase 1
15828829 10.1021/jm049011j Cholinesterase 1
17417631 10.1038/nchembio873 Unchecked 1
21733699 10.1016/j.bmc.2011.06.012 Cocaine esterase 1
21733699 10.1016/j.bmc.2011.06.012 Acetylcholinesterase 1
21733699 10.1016/j.bmc.2011.06.012 Cholinesterase 1
- 10.1584/jpestics.23.113 Lycopene beta-cyclase 1
30195238 10.1016/j.ejmech.2018.09.001 ATP-citrate synthase 1
- 10.6019/CHEMBL4495564 Replicase polyprotein 1ab 1

Data from ChEMBL 36 via Core Engine