Compound Detail
CHEMBL366736
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Basic Information
| ChEMBL ID | CHEMBL366736 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WBBZSSJGTVBLGP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
10
Publications
0
Known Names
Molecular Properties
362.3
MW (Da)
3.27
ALogP
7
HBA
0
HBD
80.3
PSA (Ų)
0.49
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.75
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 4.75 | 4.75 | 17600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 17600.0 | nM | 4.75 | Effective concentration to inhibit 50% of cytomegalovirus (CMV) replication in a... | 15658867 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15658867 | 10.1021/jm034265a | Unchecked | 2 |
| 15658867 | 10.1021/jm034265a | Hepatitis B virus | 1 |
| 15658867 | 10.1021/jm034265a | Hepatitis C virus | 1 |
| 15658867 | 10.1021/jm034265a | Human alphaherpesvirus 1 | 1 |
| 15658867 | 10.1021/jm034265a | Human alphaherpesvirus 2 | 1 |
| 15658867 | 10.1021/jm034265a | Human gammaherpesvirus 4 | 1 |
| 15658867 | 10.1021/jm034265a | MT2 | 1 |
| 15658867 | 10.1021/jm034265a | CCRF-CEM | 1 |
| 20061158 | 10.1016/j.bmc.2009.12.038 | ADMET | 1 |
| 20061158 | 10.1016/j.bmc.2009.12.038 | Hepatitis B virus | 1 |
Data from ChEMBL 36 via Core Engine