Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL368082

E126
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
O=S(=O)([O-])c1cc(S(=O)(=O)[O-])c2c(N=Nc3c(O)cc(S(=O)(=O)[O-])c4ccccc34)c(O)c(S(=O)(=O)[O-])cc2c1.[Na+].[Na+].[Na+].[Na+]

Basic Information

ChEMBL ID CHEMBL368082
Name E126
Phase Preclinical
Structure Type MOL
InChI Key JHKAFWLXWFUMPM-UHFFFAOYSA-J
Parent Compound CHEMBL1207221
Active Moiety CHEMBL1207221
0
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

634.6
MW (Da)
2.81
ALogP
12
HBA
6
HBD
282.7
PSA (Ų)
0.13
QED
3
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C20H10N2Na4O14S4
MW 722.53
Aromatic Rings 4
Heavy Atoms 40
NP-Likeness -0.15

Activity Summary

IC50 3 meas.

Literature References

PubMed DOI Target Context # Activities
15050628 10.1016/j.bmcl.2004.01.079 Unchecked 1
15050628 10.1016/j.bmcl.2004.01.079 Tyrosine-protein phosphatase non-receptor type 1 1
15050628 10.1016/j.bmcl.2004.01.079 Tyrosine-protein phosphatase 1 1

Data from ChEMBL 36 via Core Engine