Compound Detail
CHEMBL3695450
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Basic Information
| ChEMBL ID | CHEMBL3695450 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FBGDBZRYMVLGTB-LRDDRELGSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
382.4
MW (Da)
0.33
ALogP
7
HBA
6
HBD
126.9
PSA (Ų)
0.41
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neprilysin CHEMBL1944 | IC50 | 7.96 | 7.96 | 11.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neprilysin | IC50 | = | 11.0 | nM | 7.96 | In Vitro Inhibition Assay: The in vitro inhibition of recombinant human neutral ... | - |
Data from ChEMBL 36 via Core Engine