Compound Detail
CHEMBL3703680
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O
Basic Information
| ChEMBL ID | CHEMBL3703680 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JNGZXGGOCLZBFB-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
490.5
MW (Da)
2.97
ALogP
4
HBA
2
HBD
90.9
PSA (Ų)
0.56
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Gamma-secretase-activating protein CHEMBL3638343 | IC50 | 8.92 | 8.92 | 1.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Gamma-secretase-activating protein | IC50 | = | 1.2 | nM | 8.92 | HTRF Biochemical Assay: Among the advantages of this Abeta 42 HTRF gamma-secreta... | - |
Data from ChEMBL 36 via Core Engine