Compound Detail
CHEMBL373333
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Basic Information
| ChEMBL ID | CHEMBL373333 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XTZSIVLWZNRBAB-CGRWFSSPSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
288.5
MW (Da)
6.33
ALogP
1
HBA
0
HBD
17.1
PSA (Ų)
0.21
QED
1
Ro5 Violations
14
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.29
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 CHEMBL4794 | IC50 | 7.29 | 7.29 | 51.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 | IC50 | = | 51.0 | nM | 7.29 | Inhibition of 100 nM capsaicin effect on intracellular [Ca2+] concentration in H... | 16000002 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16000002 | 10.1021/jm050139q | Transient receptor potential cation channel subfamily V member 1 | 1 |
Data from ChEMBL 36 via Core Engine