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Compound Detail

CHEMBL374606

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O=Cc1c(Br)c(O)c(O)c(Br)c1Br

Basic Information

ChEMBL ID CHEMBL374606
Phase Preclinical
Structure Type MOL
InChI Key KZJVMYOEIYAKSP-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

374.8
MW (Da)
3.20
ALogP
3
HBA
2
HBD
57.5
PSA (Ų)
0.45
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C7H3Br3O3
MW 374.81
Aromatic Rings 1
Heavy Atoms 13
NP-Likeness 1.19

Activity Summary

IC50 1 meas. best 4.61

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
No relevant target
CHEMBL2362975
IC50 4.61 4.61 24700.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
No relevant target IC50 = 24700.0 nM 4.61 DPPH radical scavenging activity 17602526

Literature References

PubMed DOI Target Context # Activities
17602526 10.1021/np070061b No relevant target 1
15844965 10.1021/np040199j Aldo-keto reductase family 1 member B1 1

Data from ChEMBL 36 via Core Engine