Compound Detail
CHEMBL3746307
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Basic Information
| ChEMBL ID | CHEMBL3746307 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DEAALMVARRZSEY-UHFFFAOYSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
368.4
MW (Da)
3.65
ALogP
6
HBA
2
HBD
85.2
PSA (Ų)
0.84
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas.
Ki 1 meas. best 4.25
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosinase CHEMBL3318 | Ki | 4.25 | 4.25 | 56670.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosinase | Ki | = | 56670.0 | nM | 4.25 | Competitive inhibition of diphenolase activity of mushroom tyrosinase using L-DO... | 26706112 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26706112 | 10.1016/j.bmc.2015.11.040 | Tyrosinase | 3 |
Data from ChEMBL 36 via Core Engine