Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL374854

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
c1ccc(CNc2ccnc(-n3cnc4ccncc43)n2)cc1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL374854
Phase Preclinical
Structure Type MOL
InChI Key HLJFSZSPYMQRSO-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

302.3
MW (Da)
2.82
ALogP
6
HBA
1
HBD
68.5
PSA (Ų)
0.63
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C17H14N6
MW 302.34
Aromatic Rings 4
Heavy Atoms 23
NP-Likeness -1.48

Literature References

PubMed DOI Target Context # Activities
16934457 10.1016/j.bmcl.2006.08.022 Tyrosine-protein kinase JAK2 1
16934457 10.1016/j.bmcl.2006.08.022 Tyrosine-protein kinase JAK3 1

Data from ChEMBL 36 via Core Engine