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Compound Detail

CHEMBL3754203

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COc1c(OC/C=C(\C)CC/C=C(\C)CCC=C(C)C)cc(O)c2c(=O)cc(-c3ccccc3)oc12

Basic Information

ChEMBL ID CHEMBL3754203
Phase Preclinical
Structure Type MOL
InChI Key JOZSHIGGEZXRHX-FQLUOEGPSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

488.6
MW (Da)
7.97
ALogP
5
HBA
1
HBD
68.9
PSA (Ų)
0.28
QED
1
Ro5 Violations
11
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C31H36O5
MW 488.62
Aromatic Rings 3
Heavy Atoms 36
NP-Likeness 1.50

Literature References

PubMed DOI Target Context # Activities
- 10.1039/C5MD00163C SW480 1
- 10.1039/C5MD00163C HT-29 1
- 10.1039/C5MD00163C NON-PROTEIN TARGET 1
- 10.1039/C5MD00163C HepG2 1
- 10.1039/C5MD00163C ADMET 1

Data from ChEMBL 36 via Core Engine