Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL376149

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)CN[C@H](C)[C@@H](O)[C@]1(C)O

Basic Information

ChEMBL ID CHEMBL376149
Phase Preclinical
Structure Type MOL
InChI Key CENLJTYJANLOJT-BICOPXKESA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names

Molecular Properties

749.0
MW (Da)
2.21
ALogP
14
HBA
5
HBD
177.9
PSA (Ų)
0.23
QED
2
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C38H72N2O12
MW 749.00
Aromatic Rings 0
Heavy Atoms 52
NP-Likeness 1.65

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
17467993 10.1016/j.bmc.2007.04.021 Staphylococcus aureus 2
17467993 10.1016/j.bmc.2007.04.021 Streptococcus pneumoniae 2
17467993 10.1016/j.bmc.2007.04.021 Streptococcus pyogenes 2
17467993 10.1016/j.bmc.2007.04.021 Haemophilus influenzae 1
17467993 10.1016/j.bmc.2007.04.021 Saccharomyces cerevisiae 1
21428405 10.1021/jm101593u Toxoplasma gondii 1
21428405 10.1021/jm101593u Bacillus subtilis 1
21428405 10.1021/jm101593u HFF 1

Data from ChEMBL 36 via Core Engine