Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL378191

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
O=C1C(c2c(O)[nH]c3c(Cl)cccc23)=Nc2ccccc21
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL378191
Phase Preclinical
Structure Type MOL
InChI Key NWTPNTSXENAZQO-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
7
Publications
0
Known Names

Molecular Properties

296.7
MW (Da)
3.84
ALogP
3
HBA
2
HBD
65.5
PSA (Ų)
0.72
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C16H9ClN2O2
MW 296.71
Aromatic Rings 3
Heavy Atoms 21
NP-Likeness 0.11

Literature References

PubMed DOI Target Context # Activities
16854069 10.1021/jm060314i SH-SY5Y 1
16854069 10.1021/jm060314i Glycogen synthase kinase-3 1
16854069 10.1021/jm060314i Cyclin-dependent kinase 5/CDK5 activator 1 1
16854069 10.1021/jm060314i Unchecked 1
17665890 10.1021/jm070077z Aurora kinase A 1
17665890 10.1021/jm070077z Aurora kinase B 1
17665890 10.1021/jm070077z Aurora kinase C 1

Data from ChEMBL 36 via Core Engine