Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL378359

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CN1C(=O)c2c(c3c4ccccc4[nH]c3c3ccccc23)C1=O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL378359
Phase Preclinical
Structure Type MOL
InChI Key WGGWPASYKMPMMT-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

300.3
MW (Da)
3.70
ALogP
2
HBA
1
HBD
53.2
PSA (Ų)
0.50
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C19H12N2O2
MW 300.32
Aromatic Rings 4
Heavy Atoms 23
NP-Likeness 0.23

Literature References

PubMed DOI Target Context # Activities
16420063 10.1021/jm050945x Unchecked 2
16420063 10.1021/jm050945x Glycogen synthase kinase-3 1
16420063 10.1021/jm050945x CEM/C2 1
16420063 10.1021/jm050945x CCRF-CEM 1
16420063 10.1021/jm050945x Cyclin-dependent kinase 5/CDK5 activator 1 1

Data from ChEMBL 36 via Core Engine