Compound Detail
CHEMBL3793703
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3793703 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SHXURCRTXJCIFS-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
328.3
MW (Da)
2.76
ALogP
6
HBA
1
HBD
105.6
PSA (Ų)
0.65
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rhinovirus B CHEMBL612466 | EC50 | 5.66 | 5.66 | 2200.0 | 1 |
| rhinovirus B14 CHEMBL613759 | EC50 | 5.64 | 5.64 | 2300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rhinovirus B | EC50 | = | 2200.0 | nM | 5.66 | Antiviral activity against Human Rhinovirus B serotype 14 infected in HeLa Rh ce... | 27049678 |
| rhinovirus B14 | EC50 | = | 2300.0 | nM | 5.64 | Antiviral activity against Human rhinovirus B14 infected in human HeLa Rh cells ... | 28987610 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28987610 | 10.1016/j.ejmech.2017.09.036 | Unchecked | 2 |
| 27049678 | 10.1016/j.ejmech.2016.03.049 | Rhinovirus B | 1 |
| 27049678 | 10.1016/j.ejmech.2016.03.049 | ADMET | 1 |
| 28987610 | 10.1016/j.ejmech.2017.09.036 | rhinovirus B14 | 1 |
Data from ChEMBL 36 via Core Engine