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Compound Detail

CHEMBL385488

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O=C(Cn1c(=O)ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c1=O)c1ccccc1

Basic Information

ChEMBL ID CHEMBL385488
Phase Preclinical
Structure Type MOL
InChI Key BTNPGBJHKRUBLX-DTZQCDIJSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

602.3
MW (Da)
-1.14
ALogP
14
HBA
6
HBD
270.6
PSA (Ų)
0.13
QED
3
Ro5 Violations
11
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C17H21N2O16P3
MW 602.28
Aromatic Rings 2
Heavy Atoms 38
NP-Likeness 0.66

Literature References

PubMed DOI Target Context # Activities
17125260 10.1021/jm060848j P2Y purinoceptor 6 3
17125260 10.1021/jm060848j P2Y purinoceptor 2 3
17125260 10.1021/jm060848j P2Y purinoceptor 4 3

Data from ChEMBL 36 via Core Engine