Compound Detail
CHEMBL389656
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Basic Information
| ChEMBL ID | CHEMBL389656 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IKZDMJSZEMDIMC-UHFFFAOYSA-N |
2
Targets
3
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
312.4
MW (Da)
5.12
ALogP
2
HBA
2
HBD
48.9
PSA (Ų)
0.55
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 4.13
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Maltase-glucoamylase CHEMBL2074 | IC50 | 4.13 | 4.13 | 74320.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 4.13 | 4.13 | 74300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 74300.0 | nM | 4.13 | Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alp... | 31679980 |
| Maltase-glucoamylase | IC50 | = | 74320.0 | nM | 4.13 | Inhibition of alpha-glucosidase (unknown origin) | 38508120 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17079151 | 10.1016/j.bmc.2006.10.025 | Mus musculus | 10 |
| 17079151 | 10.1016/j.bmc.2006.10.025 | Rattus norvegicus | 1 |
| 29429576 | 10.1016/j.bmc.2018.01.029 | Acetylcholinesterase | 1 |
| 29429576 | 10.1016/j.bmc.2018.01.029 | Cholinesterase | 1 |
| 29429576 | 10.1016/j.bmc.2018.01.029 | Brain | 1 |
| 31679980 | 10.1016/j.bmc.2019.115148 | Unchecked | 1 |
| 38508120 | 10.1016/j.ejmech.2024.116332 | Maltase-glucoamylase | 1 |
Data from ChEMBL 36 via Core Engine