Compound Detail
CHEMBL39185
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Basic Information
| ChEMBL ID | CHEMBL39185 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HWVSNQLIQVRAMF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
199.2
MW (Da)
-0.10
ALogP
3
HBA
3
HBD
100.6
PSA (Ų)
0.58
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 4.52 | 4.52 | 30000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 30000.0 | nM | 4.52 | Percentage of glutamate maximal response was measured on Group II Metabotropic g... | 10425091 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10229625 | 10.1021/jm980571q | Metabotropic glutamate receptor 1 | 2 |
| 10229625 | 10.1021/jm980571q | Metabotropic glutamate receptor 2 | 2 |
| 10425091 | 10.1021/jm990182b | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine