Compound Detail
CHEMBL3932461
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Basic Information
| ChEMBL ID | CHEMBL3932461 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PTVFLCJAEFSYPQ-UHFFFAOYSA-N |
3
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
393.5
MW (Da)
5.16
ALogP
4
HBA
1
HBD
72.6
PSA (Ų)
0.54
QED
1
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 8.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma CHEMBL235 | EC50 | 8.4 | 8.4 | 4.0 | 1 |
| Peroxisome proliferator-activated receptor delta CHEMBL3979 | EC50 | 8.15 | 8.15 | 7.0 | 1 |
| Peroxisome proliferator-activated receptor alpha CHEMBL239 | EC50 | 5.93 | 5.93 | 1175.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma | EC50 | = | 4.0 | nM | 8.4 | Kinase Activity Assay: After 24 h treatment with the medicament, the cells were ... | - |
| Peroxisome proliferator-activated receptor delta | EC50 | = | 7.0 | nM | 8.15 | Kinase Activity Assay: After 24 h treatment with the medicament, the cells were ... | - |
| Peroxisome proliferator-activated receptor alpha | EC50 | = | 1175.0 | nM | 5.93 | Kinase Activity Assay: After 24 h treatment with the medicament, the cells were ... | - |
Data from ChEMBL 36 via Core Engine