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Compound Detail

CHEMBL3940577

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CC(C)Oc1ccccc1-n1nc(OC2CCN(S(=O)(=O)C(C)C)CC2)cc1-c1ccc(Cl)cc1

Basic Information

ChEMBL ID CHEMBL3940577
Phase Preclinical
Structure Type MOL
InChI Key RIAAESBLPRZGAK-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

518.1
MW (Da)
5.56
ALogP
6
HBA
0
HBD
73.7
PSA (Ų)
0.39
QED
2
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C26H32ClN3O4S
MW 518.08
Aromatic Rings 3
Heavy Atoms 35
NP-Likeness -1.15

Activity Summary

IC50 1 meas. best 8.15

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Voltage-gated calcium channel
CHEMBL2363032
IC50 8.15 8.15 7.0 1

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine