Compound Detail
CHEMBL39408
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Basic Information
| ChEMBL ID | CHEMBL39408 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OACXOEWXZVHOKN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
386.1
MW (Da)
1.26
ALogP
4
HBA
2
HBD
92.2
PSA (Ų)
0.60
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.33
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 CHEMBL330 | Ki | 7.33 | 7.33 | 46.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Ki | = | 46.6 | nM | 7.33 | Affinity for the glycine binding site of the NMDA receptor using [3H]- 5,7- dich... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(95)00244-N | Glutamate receptor ionotropic, NMDA 1 | 2 |
Data from ChEMBL 36 via Core Engine