Compound Detail
CHEMBL3943430
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3943430 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MJRMAEQWKBQUGE-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
324.3
MW (Da)
4.62
ALogP
2
HBA
1
HBD
46.5
PSA (Ų)
0.79
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Free fatty acid receptor 4 CHEMBL2052036 | EC50 | 5.66 | 5.66 | 2189.0 | 1 |
| Free fatty acid receptor 4 CHEMBL5339 | EC50 | 5.09 | 5.09 | 8174.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Free fatty acid receptor 4 | EC50 | = | 2189.0 | nM | 5.66 | Agonist activity at mouse GPR120 expressed in CHOK1 cells measured after 60 mins... | 27815121 |
| Free fatty acid receptor 4 | EC50 | = | 8174.0 | nM | 5.09 | Agonist activity at human GPR120 expressed in CHOK1 cells measured after 60 mins... | 27815121 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 27815121 | 10.1016/j.bmcl.2016.10.054 | Free fatty acid receptor 4 | 4 |
| 27815121 | 10.1016/j.bmcl.2016.10.054 | Free fatty acid receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine